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Tube LED outdoor wall light in black. A simple sconce with endless possibilities. This cylindrical wall Luminaire delivers powerful lumen output, either upwards or downwards, or a combination of both, depending on the configuration and application. Built to last with Die cast aluminum construction and designed with no visible hardware, this low profile highly versatile tube is perfect for your exterior and interior lighting needs. Five handsome architectural finishes will complement nearly any decor. Mounts up or down, die-cast aluminum construction, available in a single, or double light. Dimming: Elva (120V) or 0-10V, 0-10V dimming: 100%-10%, Elva dimming: 100%-15% (120V only). color temp: 3000K, CRI: 90, rated life: 70,000 hours. IP65 rated, ETL and cell wet location listed. 120V driver for 120V only. Energy Star rated, CEC Title 24 Compliant.
From the manufacturer
Energy Efficient LED
With over 70,000 rated hours
Wet Location Listed
For interior or exterior use
UL/ETL listed for use in North America
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Open access journal of the Ferrata-Storti Foundation, a non-profit organization
Open access journal of the Ferrata-Storti Foundation, a non-profit organization
2020 Impact Factor: 9.941Submission > Acceptance: 52 days
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Transducin β-like protein 1 (TBL1) plays a crucial role in controlling the stability of regulatory proteins involved in cell proliferation and autophagy induction. This study revealed that, unlike normal B cells, diffuse large B-cell lymphoma cells express abundant levels of TBL1 and its overexpression correlates with poor clinical outcome. Targeting TBL1 promoted lymphoma cell death in vitro and in vivo. These results provide the rationale for targeting TBL1 as a novel therapeutic strategy in diffuse large B-cell lymphoma.
The authors of this study developed a single-chain antibody that targets a shear gradient-specific conformation of von Willebrnad factor (VWF). In vitro studies showed that this antibody specifically reduces VWF-GPIbα binding and thrombus formation at sites of shear rate gradients but does not block platelet deposition and aggregation under constant shear rate. This characteristic places the antibody in a new class of antiplatelet therapy for selective blockade of pathological thrombus formation while maintaining normal hemostasis.
A 26-year-old female developed vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous thrombosis and bi-hemispheric hemorrhage following the first dose of the ChAdOx1 nCoV-19 vaccine. The treatment protocol, based on intravenous immunoglobulins, dexamethasone and argatroban was successful with almost complete clinical, laboratory and radiological response. This experience supports the application of an early and multidisciplinary therapeutic approach in cases of VITT, with the possibility of avoiding deaths and obtain a resolution of the syndrome.
This retrospective study compared the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) in 23 patients with hematologic malignancies transplanted from non-sibling fully matched related donors to that of patients who underwent conventional haplo-HSCT. Subjects transplanted from fully matched related donors showed trends to a higher relapse rate and lower cumulative incidence of grade II-IV acute graft-versus-host disease, but overall survival was similar. The authors concluded that individualized adjustment of the immunosuppressive treatment is reasonable for this category of patients.