Rubber protection - The pad back and the bottom of this cell phone stand are fully covered by anti-skid silicone, which can provide maximum protection for your device from any scratches and slides.
Height amp; Angle Adjustable - The height can be easily adjusted between 7.1in-8.5in, the angle is adjustable between 5°~45°, providing you comfortable viewing angle which helps to fix your posture and reduce neck amp; back strain. (Tips: for big-size devices, Please lower the height and adjust a suitable angle to get better stability).
User-Friendly Design - It is designed in such a way that you can charge it while it is mounted on the stand. Charge and use simultaneously.
Vertical amp; Horizontal Use – Great both ways for surfing the web, watching videos, reading content on your mobile hands-free.
Exquisite Workmanship - It provides the perfect angle for using facetime, viewing photos, playing games, watching movies, typing, and reading, and helps you to multi-task at the same time.
2020 Impact Factor: 9.941Submission > Acceptance: 52 days
No. 106 (11)
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Transducin β-like protein 1 (TBL1) plays a crucial role in controlling the stability of regulatory proteins involved in cell proliferation and autophagy induction. This study revealed that, unlike normal B cells, diffuse large B-cell lymphoma cells express abundant levels of TBL1 and its overexpression correlates with poor clinical outcome. Targeting TBL1 promoted lymphoma cell death in vitro and in vivo. These results provide the rationale for targeting TBL1 as a novel therapeutic strategy in diffuse large B-cell lymphoma.
The authors of this study developed a single-chain antibody that targets a shear gradient-specific conformation of von Willebrnad factor (VWF). In vitro studies showed that this antibody specifically reduces VWF-GPIbα binding and thrombus formation at sites of shear rate gradients but does not block platelet deposition and aggregation under constant shear rate. This characteristic places the antibody in a new class of antiplatelet therapy for selective blockade of pathological thrombus formation while maintaining normal hemostasis.
A 26-year-old female developed vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous thrombosis and bi-hemispheric hemorrhage following the first dose of the ChAdOx1 nCoV-19 vaccine. The treatment protocol, based on intravenous immunoglobulins, dexamethasone and argatroban was successful with almost complete clinical, laboratory and radiological response. This experience supports the application of an early and multidisciplinary therapeutic approach in cases of VITT, with the possibility of avoiding deaths and obtain a resolution of the syndrome.
This retrospective study compared the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) in 23 patients with hematologic malignancies transplanted from non-sibling fully matched related donors to that of patients who underwent conventional haplo-HSCT. Subjects transplanted from fully matched related donors showed trends to a higher relapse rate and lower cumulative incidence of grade II-IV acute graft-versus-host disease, but overall survival was similar. The authors concluded that individualized adjustment of the immunosuppressive treatment is reasonable for this category of patients.